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» Can metronidazole be taken with dairy products? How to take the drug Metronidazole - composition, mechanism of action, release form, dosage for children and adults. Metronidazole - Pharmacological action

Can metronidazole be taken with dairy products? How to take the drug Metronidazole - composition, mechanism of action, release form, dosage for children and adults. Metronidazole - Pharmacological action

The active substance Metronidazole has antimicrobial and antiprotozoal effects against:

  • Peptococcus niger.;
  • Bacteroides spp., including Bacteroides distasonis, Bacteroides thetaiotaomicron, Bacteroides fragilis, Fusobacterium spp., Bacteroides ovatus, Bacteroides vulgatus;
  • Entamoeba histolytica;
  • Clostridium spp.;
  • Trichomonas vaginalis;
  • Eubacterium spp.;
  • Peptostreptococcus spp;
  • Metronidazole in combination with amoxicillin is also effective against Helicobacter pylori.

    According to the instructions, Metronidazole causes sensitization to alcohol, increases the sensitivity of tumors to radiation and stimulates reparative processes.

    Release form

    Metronidazole is available in various dosage forms:

  • Flat-cylindrical white tablets Metronidazole, 250 mg of active ingredient, 20 pieces in jars, 10 pieces in a blister;

  • Metronidazole suppositories containing 0.1 g of metronidazole in each suppository. 10 candles per package;
  • A yellowish transparent solution for infusion in polyethylene bottles containing 500 mg of active substance;
  • Colorless 1% vaginal gel. 100 g of gel contains 1 g of active ingredient. In aluminum tubes of 30 g, complete with applicator.
  • Indications for use of Metronidazole

    According to the instructions, Metronidazole is used to treat:

  • Infections caused by Bacteroides species - abdominal cavity, including peritonitis and liver abscess, pelvic organs, including endomyometritis, endometritis, vaginal vault infections after surgery, fallopian tube and ovarian abscess, and soft tissue and skin infections;
  • Infections caused by Bacteroides and Clostridium species – sepsis;
  • Gastritis or duodenal ulcers that are caused by Helicobacter pylori;
  • Protozoal infections - intestinal amebiasis, balantidiasis, extraintestinal amebiasis, trichomoniasis, including amoebic liver abscess, trichomonas vaginitis, giardiasis, cutaneous leishmaniasis, trichomonas urethritis;
  • Infections caused by Bacteroides spp., including B. distasonis, B. fragilis, B. vulgalus B. ovatus, B. thetaiotaomicron - infections of the joints, bones, central nervous system, including brain abscess and meningitis, as well as pneumonia, bacterial endocarditis, empyema and lung abscess;

  • Alcoholism;
  • Pseudomembranous colitis, which is associated with the use of antibiotics.
  • Metronidazole is also used according to the instructions:

  • For the prevention of postoperative complications in the peri-rectal area and colon, gynecological operations and appendectomy;
  • For radiation therapy in oncology, as a radiosensitizing agent.
  • Metronidazole suppositories are used for urogenital trichomoniasis and bacterial vaginitis, which are caused by microorganisms sensitive to the drug.

    Contraindications

    According to the instructions, Metronidazole is contraindicated for use in:

  • Organic lesions of the central nervous system, including epilepsy;
  • Leukopenia, incl. in the anamnesis;
  • Liver failure if large doses are prescribed.
  • The first trimester of pregnancy, hypersensitivity to the components of the drug and the lactation period are contraindications to the use of Metronidazole.

    Metronidazole is prescribed with caution in the second and third trimesters of pregnancy, as well as in cases of renal or liver failure.

    Instructions for use of Metronidazole

    Metronidazole tablets are taken after meals. The dosage and duration of treatment depends on the disease:

  • For trichomoniasis - 2 tablets of Metronidazole twice a day for 10 days. Also, during treatment, it is necessary to use Metronidazole suppositories intravaginally, 2 suppositories twice a day - in the evening and in the morning. In this case, Metronidazole suppository therapy is recommended to begin at the beginning of the menstrual cycle, and douching should be avoided during this period. If necessary, the course of treatment for trichomoniasis can be repeated after a month. For children, the dosage of the drug depends on age - at 2-5 years old, 250 mg per day is prescribed, at 5-10 years old - up to 375 mg, older - up to 500 mg per day;

  • For giardiasis, Metronidazole is used for 5-7 days twice a day, 2 tablets;
  • If a cyst is detected with asymptomatic amebiasis, take 2 Metronidazole tablets up to 3 times a day for 5-7 days;
  • For chronic amebiasis, the daily dose of Metronidazole is 1.5 g, which can be divided into three doses. Take within 5-10 days;
  • For acute amoebic dysentery - until symptoms stop, take 2.25 g, divided into 3 doses;
  • For liver abscess in combination with tetracycline antibiotics and other methods of therapy - a maximum of 2.5 g of Metronidazole for 3-5 days;
  • For balantidiasis - for 5-6 days, 750 mg 3 times a day;
  • For ulcerative stomatitis - 2 Metronidazole tablets twice a day, up to 5 days;
  • To treat chronic alcoholism, take 2 Metronidazole tablets per day for up to six months.
  • In case of severe renal impairment, the daily dose should be halved.

    If it is impossible to use Metronidazole orally, as well as in severe cases of infection, the drug is used intravenously.

    The usual dose is 500 mg, but not more than 4 g per day. When improvement occurs, switch to oral administration of the drug.

    Side effects

    According to reviews, Metronidazole may cause the following side effects:


  • Diarrhea, anorexia, constipation, nausea, glossitis, dry mouth, vomiting, metallic taste in the mouth, pancreatitis;
  • Cystitis, dysuria, urinary incontinence, polyuria, candidiasis, red-brown coloring of urine;
  • Dizziness and impaired coordination of movements, confusion, irritability, depression, hallucinations, increased excitability;
  • Urticaria, fever, skin rash, skin flushing, nasal congestion, arthralgia;
  • Neutropenia and leukopenia.
  • According to reviews, Metronidazole most often causes insomnia, headache, and weakness.

    According to reviews, Metronidazole causes intestinal colic, stomatitis, convulsions, ataxia and fever much less frequently.

    Caution must be exercised when using Metronidazole simultaneously with other drugs due to the possibility of developing undesirable side effects. According to reviews, it is not recommended to use alcohol during Metronidazole therapy due to the possibility of developing neurological symptoms and the appearance of spastic abdominal pain, vomiting and nausea.

    Storage conditions

    The drug is available only with a doctor's prescription. The shelf life of Metronidazole tablets and suppositories is 2 years.

    Source: zdravo2020.ru

    zdravo2020.ru

    General information about the drug

    The active ingredient is Metronidazole 250 mg. The medicine is available in white tablets and in the form of a gel and solution for infusion.

    How does Metronidazole affect the body and what does it help with? A distinctive feature is the rapid penetration of the active components into the cell, as well as tissues and internal organs. The medicine, penetrating inside the body, begins to interact with the DNA of the cells that caused the disease. The spread of infections is stopped.

    Since the active substances of Metronidazole harm only bacterial cells, the human body does not suffer. To achieve results, high doses of medication are often prescribed. If necessary, the dosage is reduced. The tablets are not a food supplement.

    The drug penetrates almost completely into the blood. After just a couple of hours, the effect of the treatment composition is observed. The highest concentrations are observed in saliva, genital secretions, lungs, skin, liver and brain. After 7 hours, the drug is almost completely excreted in the urine.

    The drug is dispensed in pharmacies only with a doctor's prescription. The shelf life varies from manufacturer to manufacturer and can be 3 or 5 years. The average price for the drug in tablet form is about 100 rubles.

    Cases in which it is advisable to use the medication

    The scope of the drug Metronidazole is wide. As a result of taking the drug, pain goes away, nausea goes away, stool normalizes, and the patient’s general well-being improves. What does Metronidazole help with:

    1. Infections caused by protozoan pathogens: amoebic dysentery, liver abscess, giardiasis, trichomoniasis, trichomonas vaginitis or urethritis.
    2. Diseases caused by pathogenic bacteria of the bacteroides species can be cured. Joints and bones, the central nervous system, and the brain may be affected (meningitis, abscess).

    3. The medicine is used in the treatment of diseases caused by clostridia, peptococci and peptostreptococci. Against their background, peritonitis, liver abscess, endometritis, and ovarian abscess can develop.
    4. Metronidazole can treat stomach and duodenal ulcers caused by the bacterium Helicobacter pylori.
    5. The medication treats gastritis and duodenitis.
    6. Prescribed for prophylaxis after surgery.
    7. Metronidazole is taken for cancer. The drug increases the sensitivity of tumors to radiation.

    Why can women be prescribed Metronidazole? Women are more susceptible to genital infections. This is due to the physiological characteristics of the structure of the body. These pills are often prescribed to solve gynecological problems. Prescribed for bacterial vaginosis, vaginitis, cystitis, thrush, and inflammation of the epididymis.

    Patient reviews are positive. Tatyana, 41 years old: “I took this drug for gynecological diseases. There were no side effects, and the price was pleasantly surprising. I used tablets for cystitis.”

    For what diseases can medication be prescribed for men? For men it is prescribed for trichomoniasis, amoebiasis, giardiasis. The reason for prescribing the drug is a lung or liver abscess, pneumonia, meningitis, peritonitis.

    The male genital organs are damaged by infectious processes. The prostate, seminal vesicles, testicles and their appendages are affected. In these cases, it is advisable to use Metronidazole for men.


    The reviews from men are also mostly positive. Igor, 34 years old: “I take the drug as part of complex therapy for giardiasis. Already on the second day, the symptoms of the disease decreased. They prescribed me to drink it for 7 days.”

    Precautions

    During treatment with Metronidazole, contraindications to the drug should be taken into account:

    • high sensitivity to at least one of the components of the drug;
    • decreased level of leukocytes in the blood;
    • epilepsy and other disorders related to the central nervous system;
    • the first three months of bearing a child;
    • breastfeeding period.

    Take with caution for liver and kidney diseases, patients with diabetes mellitus. Prescription in the second and third trimester of pregnancy is carried out under the strict supervision of a doctor.

    If you take Metronidazole for a long time or do not follow the recommendations of a specialist, adverse reactions may develop, which manifest themselves in the form of rash, hives, and nasal congestion. There may be attacks of dizziness and headaches. Sometimes there is loss of consciousness, irritability, sleep disturbance. Symptoms of intoxication: nausea, vomiting, bowel dysfunction, loss of appetite. In some cases, candidiasis and cystitis develop.

    Concomitant use with other medications can lead to allergic reactions and constant constipation. Therefore, it is important to tell the doctor about the medications the patient is taking. Can it be combined with antibiotics? The drug can be taken in parallel with antibacterial drugs.


    An overdose can lead to poisoning. Pain in the abdomen and stomach develops, nausea and vomiting occur, and convulsions appear. Worried about weakness, drowsiness, lack of appetite.

    How to take Metronidazole correctly? There are several important features:

    1. The risk of side effects increases if you simultaneously drink alcoholic beverages.
    2. It should not be prescribed together with Amoxicillin to patients under 18 years of age.
    3. While taking the pills, the urine becomes dark in color.
    4. When taking the drug for a long time, your blood counts should be checked.
    5. During the treatment of sexually transmitted infections, sexual intercourse is excluded. If a diagnosis is made, both partners should undergo treatment.
    6. If after treatment of giardiasis the symptoms still persist, then you should retake the tests three weeks after the last tablet. Sometimes there are cases where the disease has been successfully cured, but the symptoms of helminthic infestation remain.
    7. For the entire course of treatment, activities that require increased concentration, including driving, should be excluded. The decrease in reaction occurs immediately after discontinuation of the drug.

    Only a doctor, taking into account individual characteristics, can replace the drug with another Metronidazole analogue that has a similar effect. The following medications may be prescribed: Trichopolum, Metrogyl, Ornidazole, Dazolic.

    parazitycheloveka.ru

    Clinical and pharmacological group

    Antiprotozoal drug with antibacterial activity.

    Conditions for dispensing from pharmacies

    Dispensed with a doctor's prescription.

    Prices

    How much does Metronidazole cost? The average price in pharmacies is 20 rubles.

    Release form and composition

    Metronidazole tablets are white or white with a yellow-green tint, flat-cylindrical in shape with a dividing line. The main active ingredient of the drug is metronidazole, its content in one tablet is 250 mg. It also includes auxiliary components:

    • Talc.
    • Potato starch.
    • Stearic acid.

    Metronidazole tablets are packaged in blister packs of 10 and 20 pieces. A cardboard pack contains from 1 to 10 blisters with the corresponding number of tablets and instructions for use of the drug.

    Pharmacological effect

    The antibacterial drug has a special mechanism of action, which consists of activating the biochemical reduction of the fifth nitro group using intracellular transport proteins of protozoa and anaerobic mechanisms, as described in the instructions for use. Restored cells interact with the DNA of microorganisms, which is accompanied by inhibition of the synthesis of their nucleic acid. As a result, immediate death of bacteria occurs.

    The instructions for the antibacterial tablet drug contain information that it is effective against gram-negative and some positive anaerobes. The minimum inhibitory concentration for the destruction of pathogenic microorganisms is considered to be a dose of 0.125-6.25 mcg/ml. The antibiotic, together with amoxicillin, is active against Helicobacter pylori, since such a combination of drugs helps suppress the development of resistance.

    The drug "Metronidazole" is not active against aerobic microorganisms and facultative forms of anaerobes. It should be noted that in the presence of mixed flora, this drug acts synergistically with antibacterial agents that are effective against simple aerobes. Metronidazole affects tumors, increasing their sensitivity to radiation. The drug has a disulfiram-like effect, causing sensitization to alcohol, and also turns out to be a stimulator of reparative processes.

    Indications for use

    What does it help with? Metranidazole is used in the following cases:

    • with alcoholism;
    • for the treatment of gastritis and duodenal ulcers;
    • for infections caused by Bacteroides spp. (infections of the abdominal cavity, pelvic organs, infectious diseases of soft tissues and skin, abscess of the ovaries and fallopian tubes, infections of the vaginal vault after surgery);
    • for protozoal infections (intestinal or extraintestinal amebiasis, balantidiasis, cutaneous leishmaniasis, trichomoniasis, trichomonas urethritis, giardiasis, trichomonas vaginitis);
    • for the treatment of infectious diseases of the central nervous system, bones and joints caused by the activity of Bacteroides spp.;
    • with pseudomembranous colitis associated with the use of antibiotics; for the prevention of postoperative complications during appendectomy, gynecological surgical interventions, operations on the peri-rectal area.

    Metronidazole suppositories are used to treat urogenital trichomoniasis and bacterial vaginitis caused by microorganisms sensitive to the drug.

    Contraindications

    • lactation period;
    • leukopenia (including history);
    • organic lesions of the central nervous system (including epilepsy);
    • hypersensitivity to the composition of the drug Metronidazole, which may cause side effects;
    • liver failure (if large doses are prescribed);
    • pregnancy (1st trimester).

    Use during pregnancy and lactation

    If it is necessary to prescribe Metronidazole to the mother, it is advisable to transfer the infant to artificial feeding.

    Dosage and method of administration

    The instructions for use indicate that Metronidazole tablets are taken orally, during or after meals (or with milk), without chewing.

    1. For giardiasis - 15 mg/kg/day in 3 divided doses for 5 days.
    2. For giardiasis - 500 mg 2 times a day for 5-7 days. Children under 1 year old - 125 mg/day, 2-4 years old - but 250 mg/day, 5-8 years old - 375 mg/day, over 8 years old - 500 mg/day (in 2 doses). The course of treatment is 5 days.
    3. For chronic amoebiasis, the daily dose is 1.5 g in 3 divided doses for 5-10 days.
    4. Adults: for asymptomatic amebiasis (if a cyst is detected), the daily dose is 1-1.5 g (500 mg 2-3 times a day) for 5-7 days.
    5. For acute amoebic dysentery - 2.25 g in 3 doses until symptoms stop.
    6. For balantidiasis - 750 mg 3 times a day for 5-6 days.
    7. For liver abscess - the maximum daily dose is 2.5 g in 1 or 2-3 doses, for 3-5 days, in combination with antibiotics (tetracyclines) and other methods of therapy. Children 1-3 years old - 1/4 adult dose, 3-7 years old - 1/3 adult dose, 7-10 years old - 1/2 adult dose.
    8. For pseudomembranous colitis - 500 mg 3-4 times a day.
    9. For ulcerative stomatitis, adults are prescribed 500 mg 2 times a day for 3-5 days; In this case, the drug is not indicated for children.
    10. When treating anaerobic infection, the maximum daily dose is 1.5-2 g.
    11. In the treatment of chronic alcoholism, 500 mg/day is prescribed for a period of up to 6 (not more than) months.
    12. To prevent infectious complications - 750-1500 mg/day in 3 doses 3-4 days before surgery, or 1 g once on the 1st day after surgery. 1-2 days after surgery (when oral administration is already allowed) - 750 mg/day for 7 days.
    13. For eradication of Helicobacter pylory - 500 mg 3 times/day for 7 days (as part of combination therapy, for example, combination with amoxicillin 2.25 g/day).
    14. For trichomoniasis - 250 mg 2 times / day for 10 days or 400 mg 2 times / day for 5-8 days. Women must additionally be prescribed Metronidazole in the form of vaginal suppositories or tablets. If necessary, you can repeat the course of treatment or increase the dose to 0.75-1 g/day. Between courses you should take a break of 3-4 weeks with repeated control laboratory tests. An alternative treatment regimen is to prescribe 2 g once to the patient and his sexual partner. Children 2-5 years old - 250 mg/day; 5-10 years - 250-375 mg/day, over 10 years - 500 mg/day. The daily dose should be divided into 2 doses. The course of treatment is 10 days.

    In case of severe renal dysfunction (creatinine clearance less than 10 ml/min), the daily dose should be halved.

    Side effects

    The drug has a number of side effects on many body systems.

    1. Digestive problems may include vomiting, nausea, dry mouth, glossitis, and pancreatitis.
    2. From the genitourinary system there may be cystitis, candidiasis, urinary incontinence, staining of urine.
    3. Hives, itching, and hyperemia may occur on the skin.
    4. The nervous system may respond with headache, insomnia, peripheral neuropathy, hallucinations, confusion, irritability, excitability, impaired motor coordination, ataxia, and depression.

    All of the above signs refer to symptoms of intoxication; if they occur, you should urgently stop treatment, then rinse your stomach or skin and consult a doctor. Symptoms of giardiasis may appear with successful treatment of the pathology; they need to be rechecked every 3-4 days 3 times.

    Overdose

    If an overdose of the drug occurs, the patient may experience ataxia, nausea, and vomiting. In cases of severe overdose, peripheral neuropathy as well as seizures may occur.

    In this case, symptomatic therapy is practiced; there is no specific antidote.

    Special instructions

    Before you start using the drug, read the special instructions:

    1. Colors urine dark.
    2. In combination with amoxicillin, it is not recommended for use in patients under 18 years of age.
    3. With long-term therapy, it is necessary to monitor the blood picture.
    4. With leukopenia, the possibility of continuing treatment depends on the risk of developing an infectious process.
    5. The appearance of ataxia, dizziness and any other deterioration in the neurological status of patients requires cessation of treatment.
    6. May immobilize treponemes and lead to a false-positive Nelson test.
    7. When treating trichomonas vaginitis in women and trichomonas urethritis in men, it is necessary to abstain from sexual activity. Simultaneous treatment of sexual partners is mandatory. Treatment does not stop during menstruation. After treatment for trichomoniasis, control tests should be carried out during three consecutive cycles before and after menstruation.
    8. After treatment of giardiasis, if symptoms persist, after 3-4 weeks, perform 3 stool tests at intervals of several days (in some successfully treated patients, lactose intolerance caused by infestation may persist for several weeks or months, resembling the symptoms of giardiasis).

    Alcohol compatibility

    During the treatment period, ethanol intake is contraindicated (a disulfiram-like reaction may develop: cramping abdominal pain, nausea, vomiting, headache, sudden flushing of the face).

    Drug interactions

    When using the drug, it is necessary to take into account interactions with other medications:

    1. Sulfonamides enhance the antimicrobial effect of metronidazole.
    2. Strengthens the effect of indirect anticoagulants, which leads to an increase in the time of prothrombin formation.
    3. Similar to disulfiram, it causes ethanol intolerance.
    4. When taken simultaneously with lithium preparations, the concentration of the latter in plasma may increase and symptoms of intoxication may develop.
    5. It is not recommended to combine with non-depolarizing muscle relaxants (vecuronium bromide).
    6. Cimetidine inhibits the metabolism of metronidazole, which may lead to an increase in its concentration in the blood serum and an increased risk of side effects.
    7. The simultaneous administration of drugs that stimulate microsomal oxidation enzymes in the liver (phenobarbital, phenytoin) can accelerate the elimination of metronidazole, resulting in a decrease in its plasma concentration.
    8. Concomitant use with disulfiram can lead to the development of various neurological symptoms (the interval between prescriptions is at least 2 weeks).

    Reviews

    We have selected some reviews from people who have taken the drug Metronidazole:

    1. Catherine. I took 2 tablets in the morning and evening along with doxycycline for 7 days. At first I didn’t understand why I was dizzy, making noise, making me stagger and feel sick. I read about the horror side effects, and I definitely collected half of them. I hope it really helps and I didn’t suffer in vain.
    2. Elena. For anyone who has noticed side effects from treatment with the drug: keep in mind that such symptoms can be caused by intoxication with the decay products of Giardia, which are killed by metronidazole, perhaps you just have chronic latent giardiasis...
    3. Karina. I used metronidazole for severe acne, my cosmetologist prescribed it for me, I liked the effect, there were much fewer pimples. I just felt a little nauseous after taking it, and then the nausea somehow went away on its own.
    4. Tatiana. Metronidazole is a lifesaver drug for me. I always have it in my purse. Like many women, I often suffer from cystitis. It happens that this illness takes you by surprise at work. In this case, I have metronidazole, and I know that it will definitely help. This is an old, proven remedy that my mother used. It is an antimicrobial and anti-inflammatory medicine. Tablets are round in color, slightly yellow. The taste is very bitter, and this is the only negative for me. When cystitis worsens, it helps me within 20 minutes after taking it. The only thing I would like to say is that, like any effective antimicrobial medicine, metronidazole also kills beneficial microflora, therefore, to avoid problems with the intestines, it is advisable to drink bifidobacteria after taking it.

    Analogs

    Structural analogues of the active substance:

    • Bacimex;
    • Deflamon;
    • Klion;
    • Metrovagin;
    • Metrogil;
    • Metroxan;
    • Metrolacare;
    • Metron;
    • Metronidazole Nycomed;
    • Metronidazole-AKOS;
    • Metronidazole-Altpharm;
    • Metronidazole-LecT;
    • Metronidazole-UBF;
    • Metronidal;
    • Metroseptol;
    • Orvagil;
    • Rosamet;
    • Rosex;
    • Cyptrogyl;
    • Tricho-PIN;
    • Trichobrol;
    • Trichopolum;
    • Trichosept;
    • Flagyl;
    • Efloran.

    Before using analogues, consult your doctor.

    Storage conditions and shelf life

    The tablets should be kept in places with low humidity, shielded from sunlight, at a temperature of ≤ 25°C. Keep away from children!

    The shelf life is 2 years from the date of issue; do not use after the expiration date.

    simptomy-treatment.net

    What is this

    Metronidazole is a drug with activity against protozoan microorganisms, anaerobic and some gram-positive bacteria.

    This drug is used not only against acne, but also in the treatment of other diseases.

    But Metronidazole for acne is especially popular, as it allows you to effectively get rid of inflamed rashes if they are caused by microorganisms sensitive to this substance.

    It is often prescribed to treat teenage acne.

    How it works

    Metronidazole is integrated into the respiratory chain of pathogens, which also cause rashes on the face. It disrupts this function, which leads to the rapid death of protozoa and anaerobes.

    It is used as monotherapy and in combination with other antimicrobial drugs.

    As part of complex therapy, the drug is active even against bacteria that are resistant to it.

    Therefore, it is often combined with other antibacterial agents.

    The main properties of Metronidazole are as follows:

    • antiprotozoal (active against protozoan microorganisms);
    • antibacterial;
    • trichomonacid;
    • antiulcer.

    When taken simultaneously with Amoxicillin, Metronidazole is active against Helicobacter pylori, which causes gastric ulcers. It is also used as an anti-alcohol agent, which creates an aversion to alcohol.

    Despite its antibacterial properties, Metronidazole does not belong to the category of antibiotics because it acts in a specific way.

    This allows it to be prescribed in a larger number of cases and combined with antibacterial drugs.

    Release form

    Depending on the problem, the doctor selects the drug in the form that will be most effective.

    Metronidazole is available in three forms:

    • pills– for oral administration;
    • gel– dental and for external use;
    • injection solution.

    To combat acne, Metrogyl ointment (the active substance is metronidazole) and tablets are used. Moreover, the drug in tablets is taken not only internally, as prescribed by the instructions, but also externally as part of masks, talkers, and facial lotions.

    The price of Metronidazole is quite affordable, and in any form.

    You can verify this based on data from Moscow pharmacies:

    Indications

    Depending on the form, the range of indications for Metronidazole is quite wide.

    It is used to treat:

    • rosacea, juvenile, vulgar acne caused by microorganisms (Metrogil gel);
    • infectious and inflammatory diseases of the oral mucosa (Metrogil Denta gel);
    • protozoal and anaerobic infections of various body systems, postoperative infections and their prevention, sepsis, abscesses (metronidazole tablets and injection solution).

    For acne, the doctor can prescribe not only a gel, but also tablets if the acne is moderate or severe.

    Video: “Causes of acne and the most effective remedy for acne”

    Features of using the gel

    The safest form of taking Metronidazole for acne is the gel.

    But you still need to first consult with your doctor about the need to use this particular drug.

    • Instructions for use of Metrogyl gel (and this is Metronidazole) advises applying the drug to previously cleansed and dry skin. The gel is applied to problem areas in a thin layer, distributing it over the entire area of ​​the rash.
    • There is no need to rub the drug in. However, it is quickly absorbed by itself, leaving no traces on the face or in contact with clothing. This is the advantage of this dosage form over ointment or cream, the absorption rate of which is much lower.
    • Apply gel or ointment to the skin 2 times a day: in the morning and before bed. If it is necessary to use decorative cosmetics, first apply this medicine, and then, after it is completely absorbed (about half an hour), proceed to makeup. It is not advisable to wash off the gel during the day.

    A noticeable effect from the use of the gel occurs after 3 weeks of use, but the entire course of treatment with the drug lasts up to 4 months (its exact duration must be determined by the doctor).

    The gel can be used not only on the face, but also on other areas of the skin where the problem has arisen.

    How to take Metronidazole tablets for acne

    Sometimes there is a need not only for external use of Metronidazole, but also internal use.

    It occurs with severe acne; tablets are also prescribed for subcutaneous acne if they are prone to frequent relapses.

    • The doctor determines how to take the pills. This form has side effects, so taking the medicine yourself can harm yourself.
    • The usual dosage of the drug is one tablet 2 times a day, but it can be adjusted depending on age or the severity of the problem.
    • The average course of treatment is a week (from 5 to 10 days). Courses can be repeated several times, but between them there should be breaks of 3-4 weeks.

    Recipes

    But there is an alternative way to take Metronidazole tablets for acne.

    It consists of preparing medicinal mixtures based on them for external use.

    Mask

    A mask with Metronidazole is prepared as follows:

    • take white clay and powdered tablets in equal parts;
    • add a little water and mix thoroughly;
    • the mass should have a thick consistency;
    • Apply a mask to previously cleansed skin and leave for 15 minutes;
    • wash off with warm water.

    A mask with Levomycetin and Metronidazole has a stronger effect.

    • To prepare it, you will need to grind 3 tablets of one and the other into powder and dilute 20 ml of pharmacy calendula tincture.
    • This mask is applied locally, exclusively to areas with rashes.
    • Keep it on for 10-15 minutes and wash off.

    If your skin remains red after this, use a facial moisturizer.

    Lotion

    Lotion with Metronidazole tablets also gives good results.

    It is prepared like this:

    • Grind 5 tablets into powder and dilute with boiled water (no more than half a glass);
    • With the resulting mash, wipe the problem areas with a cotton pad twice a day.

    Typically, Metronidazole for acne has positive reviews, regardless of the form in which this drug was used.

    How to enhance the effect

    To make acne treatment with Metronidazole as effective as possible, you should reduce the influence of those factors that will provoke the appearance of new rashes:

    Comprehensive health care will speed up the effect of treatment and improve its outcome.

    Contraindications

    Gel for external use (Metrogyl) is contraindicated in case of individual intolerance to metronidazole and is not recommended for use by pregnant women and during breastfeeding.

    For Metronidazole in tablet form, the list of contraindications is wider. Added to it:

    • leukopenia(even if it was previously);
    • central nervous system diseases(including epilepsy);
    • liver diseases(if you need to take significant doses of the drug).

    Patients with kidney disease should take this drug under medical supervision.

    Complications

    • A complication of Metronidazole, regardless of the form of administration, can be allergic reactions of the body, which are expressed in rashes on the skin and are accompanied by itching and burning.
    • Exceeding the dosage of the drug may result in nausea and vomiting, convulsions, and loss of orientation in space.

    If you notice any manifestations after starting to use the drug, you should immediately consult a doctor.

    The drug Metronidazole MS exhibits a wide spectrum of action and has antimicrobial, antiprotozoal, and anti-inflammatory properties. Included in the group of antibiotics. To begin treatment, you need to understand the action of Metronidazole and what it helps with. When used correctly, the drug can quickly relieve the disease without causing harm to health.

    The active ingredient is mg. The medicine is available in white tablets and in the form of a gel and solution for infusion.

    How does Metronidazole affect the body and what does it help with? A distinctive feature is the rapid penetration of the active components into the cell, as well as tissues and internal organs. The medicine, penetrating inside the body, begins to interact with the DNA of the cells that caused the disease. The spread of infections is stopped.

    Since the active substances of Metronidazole harm only bacterial cells, the human body does not suffer. To achieve results, high doses of medication are often prescribed. If necessary, the dosage is reduced. The tablets are not a food supplement.

    The drug penetrates almost completely into the blood. After just a couple of hours, the effect of the treatment composition is observed. The highest concentrations are observed in saliva, genital secretions, lungs, skin, liver and brain. After 7 hours, the drug is almost completely excreted in the urine.

    The drug is dispensed in pharmacies only with a doctor's prescription. The shelf life varies from manufacturer to manufacturer and can be 3 or 5 years. The average price for the drug in tablet form is about 100 rubles.

    Cases in which it is advisable to use the medication

    The scope of the drug Metronidazole is wide. As a result of taking the drug, pain goes away, nausea goes away, stool normalizes, and the patient’s general well-being improves. What does Metronidazole help with:

    1. Infections caused by protozoan pathogens: liver abscess, giardiasis, trichomoniasis, trichomonas vaginitis or urethritis.
    2. Diseases caused by pathogenic bacteria of the bacteroides species can be cured. Joints and bones, the central nervous system, and the brain may be affected (meningitis, abscess).
    3. The medicine is used in the treatment of diseases caused by clostridia, peptococci and peptostreptococci. Against their background, peritonitis, liver abscess, endometritis, and ovarian abscess can develop.
    4. Metronidazole can treat stomach and duodenal ulcers caused by the bacterium Helicobacter pylori.
    5. The medication treats gastritis and duodenitis.
    6. Prescribed for prophylaxis after surgery.
    7. Metronidazole is taken for cancer. The drug increases the sensitivity of tumors to radiation.

    Why can women be prescribed Metronidazole? Women are more susceptible to genital infections. This is due to the physiological characteristics of the structure of the body. These pills are often prescribed to solve gynecological problems. Prescribed for bacterial vaginosis, vaginitis, cystitis, thrush, and inflammation of the epididymis.

    Patient reviews are positive. Tatyana, 41 years old: “I took this drug for gynecological diseases. There were no side effects, and the price was pleasantly surprising. I used tablets for cystitis.”

    For what diseases can medication be prescribed for men? For men it is prescribed for trichomoniasis, amoebiasis, giardiasis. The reason for prescribing the drug is a lung or liver abscess, pneumonia, meningitis, peritonitis.

    The male genital organs are damaged by infectious processes. The prostate, seminal vesicles, testicles and their appendages are affected. In these cases, it is advisable to use Metronidazole for men.

    The reviews from men are also mostly positive. Igor, 34 years old: “I take the drug as part of complex therapy for giardiasis. Already on the second day, the symptoms of the disease decreased. They prescribed me to drink it for 7 days.”

    Precautions

    During treatment with Metronidazole, contraindications to the drug should be taken into account:

    • high sensitivity to at least one of the components of the drug;
    • decreased level of leukocytes in the blood;
    • epilepsy and other disorders related to the central nervous system;
    • the first three months of bearing a child;
    • breastfeeding period.

    Take with caution for liver and kidney diseases, patients with diabetes mellitus. Prescription in the second and third trimester of pregnancy is carried out under the strict supervision of a doctor.

    If you take Metronidazole for a long time or do not follow the recommendations of a specialist, adverse reactions may develop, which manifest themselves in the form of rash, hives, and nasal congestion. There may be attacks of dizziness and headaches. Sometimes there is loss of consciousness, irritability, sleep disturbance. Symptoms of intoxication: nausea, vomiting, bowel dysfunction, loss of appetite. In some cases, candidiasis and cystitis develop.

    Concomitant use with other medications can lead to allergic reactions and constant constipation. Therefore, it is important to tell the doctor about the medications the patient is taking. Can it be combined with antibiotics? The drug can be taken in parallel with antibacterial drugs.

    An overdose can lead to poisoning. Pain in the abdomen and stomach develops, nausea and vomiting occur, and convulsions appear. Worried about weakness, drowsiness, lack of appetite.

    How to take Metronidazole correctly? There are several important features:

    1. The risk of side effects increases if you simultaneously drink alcoholic beverages.
    2. It should not be prescribed together with Amoxicillin to patients under 18 years of age.
    3. While taking the pills, the urine becomes dark in color.
    4. When taking the drug for a long time, your blood counts should be checked.
    5. During the treatment of sexually transmitted infections, sexual intercourse is excluded. If a diagnosis is made, both partners should undergo treatment.
    6. If after treatment of giardiasis the symptoms still persist, then you should retake the tests three weeks after the last tablet. Sometimes there are cases where the disease has been successfully cured, but the symptoms of helminthic infestation remain.
    7. For the entire course of treatment, activities that require increased concentration, including driving, should be excluded. The decrease in reaction occurs immediately after discontinuation of the drug.

    Only a doctor, taking into account individual characteristics, can replace the drug with another Metronidazole analogue that has a similar effect. The following may be prescribed, Metrogyl,.

    Terms of use

    The correct dosage can only be prescribed by a doctor after a series of examinations. It is forbidden to change the dose on your own. When should you take the tablets, before meals or after meals? It is recommended to take the tablets during or after meals with a small amount of water. The tablets should not be chewed or chewed.

    1. For trichomoniasis, adults need to take 500 mg per day, divided into two doses. The course of treatment lasts up to 10 days. Children from 2 to 5 years old are prescribed 250 mg, divided into two doses. In the future, the daily dosage can be increased to 370 mg.
    2. How to take pills for giardiasis? Adults are prescribed 500 mg, divided into two times, per day. The duration of treatment is no more than a week. For children from 2 to 8 years old, the dosage can be 250-375 mg per day. The course of treatment is no more than 5 days.
    3. For ulcerative colitis caused by the bacterium Helicobacter pylori, 500 mg is used three times a day. In this case, doctors often advise: “take the drug in combination with Amoxicillin.”

    Before use, you need to read the instructions to determine which anthelmintic drug can be combined with the drug.

    Metronidazole tablets will help you quickly and effectively get rid of the disease. But only if you contact a specialist in a timely manner and follow all his recommendations. Independent selection of dosage and duration of treatment can cause complications.

    Inflammatory pathologies of the stomach can occur in both acute and chronic forms, and in the absence of adequate treatment, cause serious complications that greatly impair human health. Treatment of these ailments is carried out mainly through medication, using drugs that eliminate the cause that provoked the illness.

    In the case when the onset of the disease is due to the pathogenic microorganism Helicobacter pylori colonizing the digestive organs, the course of treatment is carried out with the mandatory use of antibacterial agents.

    Metronidazole for gastritis is prescribed precisely for this purpose. With the help of this medication, the inhibition of the vital activity of pathogenic bacteria is very effective.

    Benefits of an antibiotic

    The active substance metronidazole is the main component of the drug of the same name, used for the treatment of gastritis caused by the pathogenic Helicobacter pylori microorganism. In medical practice, it was the first to be used for this purpose, but to this day this medicine has not lost its popularity.

    This antimicrobial and antiprotozoal drug is produced by the modern pharmacological industry in the form of solutions for infusions (droppers), mixtures and tablets for oral use, and suppositories.

    Most often, for gastritis, Metronidazole is prescribed in tablet form. The tablets are white with a slight greenish-yellow tint and a transverse stripe.

    In addition to the active substance, the drug contains potato starch, stearic acid and povidone. But due to the fact that this medicine has certain contraindications, when prescribing it, it is necessary to provide the gastroenterologist with the following information:

    • recent renal dialysis;
    • history of liver pathology;
    • alcohol addiction;
    • the presence of such a rare blood disease as porphyria;
    • planning or carrying a pregnancy;
    • breastfeeding a baby.

    To authorize a drug, the doctor must know what medications the person is taking. This applies not only to those drugs prescribed by specialists, but also to over-the-counter drugs, dietary supplements and homeopathic remedies.

    Analogs of Metronidazole are drugs such as Tinidazole, Ornidazole, Trichopolum and Secnidazole, which have significant differences in auxiliary components. This is an important factor when prescribing drugs to patients with a tendency to have an allergic reaction.

    Rules for using the medicine

    The components of this medication effectively prevent tissue respiration of pathogenic microorganisms and disrupt protein synthesis in their cells. After providing a therapeutic effect on the body, the active substance of Metronidazole is involved in metabolic processes, then metabolized in the liver and slowly excreted from the body (up to 80% in urine, and the rest in feces).

    Metronidazole should be taken without chewing and with plenty of water immediately after or during meals. The daily dose for adults is 6 tablets (two pieces 3 times a day).

    The course of treatment for Helicobacter gastritis with this drug usually lasts a week. Medicines such as Amosin or Amoxicillin are always prescribed together with Metronidazole, which significantly increases the effectiveness of the drug.

    Possible side effects

    Metronidazole has a very high penetrating ability, as a result of which it spreads very quickly in biological fluids (breast milk, urine, saliva). It can also concentrate in brain tissue or penetrate the placental barrier to the child a woman is carrying. This is what determines the limitations in its use and the large number of possible side effects.

    The use of Metronidazole for medicinal purposes is strictly not recommended for pregnant and lactating women, people suffering from serious blood diseases, liver or kidney failure, as well as those patients who have serious damage to the central nervous system.

    In addition, the medicine is contraindicated in children under three years of age. The main negative effects of Metronidazole are as follows:

    • On the part of the digestive organs, there is a high probability of dyspepsia, decreased appetite and the appearance of vomiting.
    • The nervous system is very susceptible to the negative effects of the drug. If, after taking the medicine, signs of insomnia, headaches or depressive mood appear for no reason, consultation with a specialist is necessary. Only he can decide whether it is advisable to continue taking this drug.
    • When using Metronidazole to treat gastritis, it is necessary to monitor the frequency of urination. If the urge to do so becomes frequent, you will need to stop taking the medication. But the changed color of urine should not cause alarm. It changes due to the fact that this medication is excreted in the urine, simultaneously changing its color.

    In the event that the course of treatment is disrupted and spontaneous use of the drug occurs, after taking it, significant disorders of the nervous system (depression, irritability, insomnia), genitourinary organs (libido and increased urge to urinate), and intestinal dysfunction may occur. in which there is a constant change in stool consistency from constipation to diarrhea.

    Metronidazole is a drug that has an antiprotozoal effect and has antimicrobial activity. This medicine is included in the list of drugs that are recognized by WHO as the most important.

    The remedy was discovered by French pharmacists in the middle of the last century. The drug became the first in the group of nitroimidazoles to be successfully used for the treatment of trichomoniasis.

    Metronidazole has a detrimental effect on bacterial flora. This effect was discovered later than the product increased its popularity.

    The product blocks the formation of nucleic acids, so the formation of a population of microorganisms stops, so they die over time. The medicine acts on pathogenic aerobic agents, that is, microorganisms that do not need oxygen to live.

    The instructions for the drug indicate a list of pathogenic agents that are sensitive to the drug. Metronidazole affects:

    • Trichomonas,
    • Amoeba,
    • Garndnerells,
    • Giardia,
    • Obligate anaerobes,
    • Some types of gram-positive microbes.

    The drug has no effect on staphylococci, streptococci and other aerobic bacteria.

    The product can also be used for sepsis and peritonitis, as well as for abscesses that are localized in the abdominal organs. In addition, Metronidazole can be used to treat various gynecological diseases.

    The product can be used in gynecology for:

    • Endometritis of various origins,
    • Asbscesses in the intimate area - ovaries or fallopian tubes,
    • Inflammation after abortion or gynecological surgery,
    • Thrush.

    The drug can also be used for the following diseases:

    1. Inflammation and abscesses of lung tissue and lungs,
    2. Abscesses localized in the brain,
    3. Meningococcal infection,
    4. Endocarditis,
    5. Purulent pathologies of bone tissue and skin.

    The instructions for use of the drug indicate that the drug can be actively used as a prophylactic, before surgical interventions on:

    • intestines,
    • inflamed appendix.

    In the intimate area, the use of Metronidazole is characterized by gynecological manipulations. The drug is also used to treat intestinal ulcers and stomach ulcers.

    Metronidazole gel is widely used in dentistry for the treatment of infectious processes. The mouth is treated with gel to eliminate inflammatory processes. Ointment with this active ingredient is also prescribed by dermatologists to treat acne.

    Metronidazole in tablet form

    Metronidazole tablets quickly enter the bloodstream from the intestines, evenly distributed throughout the systems and organs. The medicine begins to spread through biological fluids:

    1. cerebrospinal and peritoneal fluid,
    2. saliva,
    3. bile.

    In large volumes, the product enters bone tissue, breast milk, and penetrates well through the placenta. About 80% of the drug is excreted by the kidneys, the remaining 20% ​​is excreted in the bile.

    Tablets are prescribed to adults and children over 12 years of age at 7.5 mg of the drug per 1 kilogram of body weight. The average dose of the drug ranges from 250 to 6500 mg 2 times a day.

    The amount of medication depends on the stage of the pathological process and other indications. For children under 12 years of age, doctors advise taking the drug 10 mg/kg 3 times a day.

    Metronidazole in tablet form is taken after meals and should not be crushed or chewed.

    Each suppository contains 500 mg of Metronidazole. In the form of suppositories, the drug is used in the gynecological field for therapy:

    • Urethritis and vaginitis of varying severity, which are caused by nonspecific pathogens,
    • Urogenital trichomoniasis.

    Reviews say that suppositories with Metronidazole have a pronounced effect after the first procedure. The drug in the form of suppositories is inserted into the vagina. The recommended dose is 2 grams of the drug once.

    You can also administer suppositories that contain 500 mg of Metronidazole 2 times a day. The treatment course is ten days. Sexual contact is excluded for the entire duration of treatment.

    Many people wonder: is Metronidazole an antibiotic? This drug is considered a synthetically produced broad-spectrum drug. It can be argued that Metronidazole is an antimicrobial drug, but not an antibiotic.

    Antibiotics are natural substances that are created from special mushrooms. The active substance Metronidazole does not occur in nature; it is formed only with the help of pharmaceutical technologies.

    For the drug Metronidazole, side effects are expressed as:

    1. Vomiting and other disorders of the digestive system,
    2. Decreased appetite and changes in taste, changes in stool, intestinal spasms.

    Metronidazole may also cause:

    • Anxiety and sleep disturbances,
    • Dizziness,
    • Migraine,
    • Impaired peripheral sensitivity,
    • Cramps,
    • Fainting conditions,
    • Temporary hearing loss.

    The drug may also make you feel sick and there is a high risk of bad breath. Sometimes the number of leukocytes and platelets in the blood decreases.

    Reviews report that Metronidazole in any dosage form can cause an allergic reaction, for example:

    1. Itchy effect
    2. hives,
    3. Rash,
    4. Anaphylactic shock.

    Metronidazole is contraindicated during the first trimester of pregnancy. When carrying a child in later periods, the remedy can be prescribed by the woman’s attending physician, having comprehensively assessed her condition and the risks to the child.

    In most cases, people are satisfied with Metronidazole treatment. Many patients note that during therapy their urine turned brown.

    According to information from reviews, Metronidazole is considered a reliable and effective remedy that helps with serious illnesses. The frequency of side effects is negligible if you follow all the recommendations of your doctor.

    Some sources indicate that a relative contraindication may be malfunction of the pancreas. The drug should not be used because it can contribute to the exacerbation of pancreatitis, however, there is no reliable information and official clinical data about this.

    The list of relative contraindications also includes therapy with certain medications. For example, the use of Metronidazole is contraindicated during treatment with anticoagulants, for example, Warfarin with mandatory INR monitoring, the same applies to Fluorouracil.

    Metronidazole enhances their effect and can lead to a decrease in the amount of blood clotting factors and to a large accumulation of ions in the body. During therapy with Fluorulacil, lithium may accumulate.

    In addition to contraindications for use, treatment with the drug Metronidazole is limited to a certain extent by a large number of potential side effects. Some of them may go unnoticed, while others, if not removed in a timely manner, can provoke an exacerbation of certain diseases and seriously worsen the patient’s health.

    First of all, it is necessary to deal with certain complications from the central nervous system. Clinical practice knows about cases of drug-induced meningism and meningitis.

    In addition, seizures and symptoms of damage to the peripheral nerves of the extremities may develop. If the dosage is not observed, the patient may experience coordination and static disturbances, as well as severe headaches.

    Among the symptoms from the gastrointestinal tract, one can name, in addition to the well-known vomiting and nausea, spasmodic pain in the abdomen. If drug intoxication occurs, hepatotoxicity may occur.

    Side effects in relation to the urinary system are expressed in certain disorders of urination and the volume of urine excreted. It often changes not only its color, but also its density. The video in this article will provide additional information about the drug.

    Reviews about Metronidazole are mostly positive. Patients claim that the medication helps remove worms from the body in the shortest possible time and normalize the functioning of the gastrointestinal tract.

    How much do the tablets cost? In Moscow pharmacies, the price for this medicine ranges from 120 to 150 rubles. In the regions, you can purchase the medicine for 90-130 rubles. Metronidazole is a strictly controlled medicine and is therefore only available with a doctor's prescription.

    Mechanism of action and indications for use

    Metronidazole is a powerful anthelmintic and antibacterial agent. The instructions for use of the medicine state that the medicine has high bioavailability. The active components of the product are evenly distributed throughout the body.

    For mixed helminthiasis, the drug can be used. But in this case, the tablets should be combined with other anthelmintic drugs.

    Instructions for use of the drug

    How to take Metronidazole? The medicine must be taken orally with meals. It is recommended to take the medication with plenty of water. The dosage is determined taking into account the type of disease. For example, when treating trichomoniasis, the patient needs to take 2 grams of the drug once. A second course of treatment can be carried out no earlier than after 2-3 weeks.

    If the patient's chronic form of amebiasis progresses, then the dosage is 1.5 g. The frequency of administration is 2-3 times a day. For chronic amoebiasis, it is recommended to use the product for 5-10 days. A second course of treatment can be repeated after 2-4 weeks.

    For giardiasis, the patient needs to take at least 1 gram of Metronidazole per day for 5-7 days. If treatment is carried out in several cycles, then there should be an interval of 2-4 weeks between them.

    In cases where the patient has progressive infectious diseases or a duodenal ulcer due to helminthiasis, the daily dosage is 1.5 g or 2 g. The frequency of taking the medication is 2 times a day. The drug should be used for 5-7 days.

    Reviews from doctors indicate that the medication should not be taken if there is dysfunction of the hematopoietic system. If the patient suffers from leukopenia, then using Metronidazole is strictly prohibited.

    Also contraindicated for use are pregnancy (2nd and 3rd trimester), lactation period, acute renal failure, liver failure, organic damage to the central nervous system, hypersensitivity to the constituent components of the drug.

    The following side effects may occur when using the medicine:

    • Digestive system - loss of appetite, nausea, constipation, drying of the oral mucosa, the appearance of a metallic taste in the mouth. In rare cases - pancreatitis, stomatitis, glossitis.
    • Nervous system – migraine, confusion, sleep disturbances, weakness, neuropathy.
    • Hypersensitivity reactions. The patient may experience arthralgia, skin rash, fever, flushing, urticaria, and fever. If allergic reactions are not stopped in a timely manner, anaphylactic shock may develop.
    • Genitourinary system – cystitis, candidiasis, dark colored urine. In rare cases - urinary incontinence, polyuria.

    The best analogue of Metronidazole

    The mechanism of action of this drug is similar. Drug metabolites accumulate in the liver. The half-life of the active components of the product is 8-10 hours. The medicine is advisable to use in the treatment of diseases such as:

    1. Intestinal or extraintestinal amebiasis.
    2. Giardiasis.
    3. Trichomoniasis.
    4. Nonspecific vaginitis that appears against the background of helminthiasis or under the influence of anaerobic bacteria

    How to take this anthelmintic? The tablets should be taken with meals, washed down with plenty of warm water. The dosage of the drug is selected taking into account the type of disease. For giardiasis, you need to take 1 gram of the drug per day. When treating children, the dosage is 30-40 mg per 1 kg of body weight. The duration of treatment is 7 days.

    If the patient's intestinal or extraintestinal form of amebiasis progresses, the dosage is increased to 1.5-2 g per day. The duration of treatment is 7 days. If necessary, repeated drug therapy is carried out after 2-4 weeks. In cases where the patient has progressive trichomoniasis or nonspecific vaginitis, the dosage is 500-1000 mg. For these diseases, Flagyl should be taken for 5-7 days.

    The medicine is contraindicated for pregnant women, children weighing up to 16 kg, and people with hypersensitivity to the components of the drug. Also contraindicated for use is the period of lactation, hypersensitivity to gluten, organic damage to the central nervous system, renal and liver failure.

    In the video in this article, the specialist will continue the topic of the drug.

    parazity.com

    How to take Metronidazole?

    Metronidazole is usually classified as a group of antibiotics. The drug is used mainly for the treatment of diseases of the genitourinary system of infectious origin. In general, it can be used to combat all ailments caused by pathogenic microorganisms. Knowing how to take Metronidazole, you can get rid of any problem quickly enough, without harming your health at all.

    When is Metronidazole prescribed?

    This remedy has a wide spectrum of action. Metronidazole has a powerful antibacterial, anti-inflammatory and antiprotozoal effect. The drug works simply: once it enters the body, the active ingredients begin to interact with the DNA of pathogenic cells, preventing them from synthesizing nucleic acids. As a result, the infection dies.

    The medication is indicated for use for:

    • vaginitis;
    • urethritis;
    • rosacea;
    • pneumonia;
    • meningitis;
    • ulcers;
    • chronic alcoholism;
    • burns;
    • bedsores;
    • giardiasis and many other ailments.

    How and for how many days should I take Metronidazole?

    As with most other medications, the course of treatment with Metrondazole is chosen on an individual basis. Dosages and duration of use of the drug may vary depending on the form of the disease, its complexity, and the physiological characteristics of the patient.

    One thing remains unchanged - how to take Metronidazole - two hours before or after meals. The main thing is to take the drug on an empty stomach. It is advisable to consume the tablets completely, without chewing or crushing. Otherwise, too many active substances will penetrate into the blood at the same time.

    How to take Metronidazole for cystitis and demodicosis?

    Despite the fact that these diseases do not have much in common, Metronidazole can be used to treat each of them. As a general rule, adults are recommended to take two 500-milligram tablets or capsules per day. The optimal course lasts from a week to ten days. In particularly difficult cases, treatment may be delayed and the dosage increased. This happens only after agreement with a specialist.

    How to take Metronidazole for acne?

    Since Metronidazole quickly relieves inflammation and prevents the formation of scars on the skin, it is often prescribed to treat acne. The standard dose of the medication is one 250-milligram tablet twice a day.

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    womanadvice.ru

    Metronidazole is a popular antimicrobial drug

    Metronidazole is an antiprotozoal and antimicrobial drug (antibiotic) used to treat infections, in particular, it is active against Helicobacter pylori. Metronidazole is available in the form of cream, gel, oral solution, suppositories, tablets and infusion solution.

    Metronidazole is effective against pathogenic anaerobic bacteria, in particular against bacteroides and fusobacteria. Anaerobic bacteria cause a variety of infections, including peritonitis, abdominal and liver abscesses; endometritis, abscesses of the ovaries and fallopian tubes, pneumonia, lung abscess, meningitis; skin infections; bone infections and others. Metronidazole is also taken to prevent infections after gynecological and abdominal surgeries.

    Indications for use of metronidazole

    Metronidazole is indicated for use in the following cases:

    • for the treatment of protozoal infections: extraintestinal amebiasis, intestinal amebiasis, trichomoniasis, giardiasis, balantidiasis, giardiasis, cutaneous leishmaniasis, trichomonas vaginitis, trichomonas urethritis;
    • for the treatment of infections caused by bacteroids: infections of bones and joints, the central nervous system (meningitis, brain abscess, bacterial endocarditis, pneumonia, empyema and lung abscess, sepsis);
    • for the treatment of infections caused by clostridia: infections of the abdominal cavity (peritonitis, liver abscess), infections of the pelvic organs (endometritis, abscess of the fallopian tubes and ovaries, infections of the vaginal vault);
    • for the treatment of pseudomembranous colitis (associated with the use of antibiotics);
    • for the treatment of gastritis or duodenal ulcers associated with Helicobacter pylori;
    • for the prevention of postoperative complications (especially during gynecological operations);
    • during radiation therapy of patients with tumors.

    Before taking metronidazole

    Before taking metronidazole, be sure to tell your doctor:

    • about liver disease or being on kidney dialysis;
    • about pregnancy, planning pregnancy or breastfeeding;
    • about alcohol addiction;
    • about the presence of porphyria, a rare blood disease;
    • about all medications, including over-the-counter medications, homeopathic remedies and dietary supplements, that you take;
    • about allergic reactions to metronidazole or any other medicine.

    How to take metronidazole

    Read the package insert before taking metronidazole.

    Take metronidazole as directed by your doctor and the package directions.

    Take metronidazole at regular intervals until you complete your full course. Do not interrupt the course of treatment, even if you feel better.

    Take metronidazole tablets with plenty of water during or after meals. Swallow the tablets whole without chewing.

    If you forget to take the drug, take the missed dose of Meridia as soon as you remember. If it is near the time of your next dose, do not take the missed dose and continue to follow your treatment schedule. Do not take an extra dose to make up for a missed dose.

    How to use metronidazole suppositories

    • Remove the suppository (anal suppository) from the package.
    • It is easier to insert the suppository if you sit down or lean forward.
    • Using your finger, gently push the suppository as deep as possible into the rectum, with the pointed tip facing forward.
    • Do not move for a while to allow the suppository to set.
    • Wash your hands with soap.

    Side effects of metronidazole

    Side effects of metronidazole vary from person to person; The following side effects are not observed in all cases:

    • diarrhea;
    • decreased appetite;
    • nausea;
    • vomit;
    • intestinal colic;
    • constipation;
    • dryness and metallic taste in the mouth;
    • stomatitis;
    • pancreatitis;
    • dizziness;
    • impaired coordination of movements;
    • confusion;
    • irritability;
    • depression;
    • increased excitability;
    • weakness;
    • insomnia;
    • headache;
    • convulsions;
    • hallucinations;
    • allergic reactions (urticaria, skin rash, skin flushing, nasal congestion, fever);
    • dysuria;
    • cystitis;
    • polyuria;
    • urinary incontinence;
    • candidiasis;
    • thrombophlebitis (pain, hyperemia or swelling at the injection site);
    • neutropenia;
    • leukopenia.

    Use during pregnancy and breastfeeding

    Since metronidazole is found in fairly significant concentrations in breast milk, its use is contraindicated for nursing mothers. It is also recommended, if possible, to avoid taking metronidazole in the first trimester of pregnancy, since its effect on embryo development has not been sufficiently studied.

    Article tags:

    www.womenhealthnet.ru

    When and why is Metronidazole prescribed?

    • Properties of metronidazole
    • Prescription and administration of Metronidazole
    • Metronidazole in gynecology
    • Questions about taking the drug to treat certain diseases?
    • Side effects and contraindications to the use of Metronidazole
    • Conclusion on the topic

    Almost every person sooner or later faces the need to get rid of an infection. Therefore, many people have a question regarding the drug Metronidazole: what is it prescribed for, will it help cure this or that ailment? Indeed, the drug relieves health problems when an infection enters the body. But before you decide to be treated with this remedy, it is better to get the necessary information without being content with rumors.

    Properties of metronidazole

    Metronidazole is an antiprotozoal and antimicrobial agent. The question arises: Is Metronidazole an antibiotic or not? This antimicrobial drug is not an antibiotic, because natural antibiotic substances are obtained from fungi. Metronidazole is produced synthetically through chemical reactions. In pharmacies it can be found in the form of tablets, in liquid form in ampoules, it is included in gels, creams, solutions, capsules, suppositories. It is used orally, intravenously, rectally and intravaginally, as well as topically in the case of metronidazole-based gels. The method of administration and dose are determined by the doctor.

    The tablets are taken after meals, washed down with enough water.

    When using gels and creams, care must be taken to avoid contact with the eyes. If this fails, you should rinse your eye thoroughly with running water.

    The drug has the property of being quickly absorbed, penetrating into the tissues and cells of the body. On average, it is taken for no more than 10 days. But this depends on the nature of the disease and the individual characteristics of the body, which are determined by the doctor.

    Metronidazole can be used with other antibiotics.